HMGB2 antibody (Middle Region)

Catalog No. ABIN2787575

This anti-HMGB2 antibody is a Rabbit Polyclonal antibody detecting HMGB2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for HMGB2 antibody (Middle Region) (ABIN2787575)

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGB2 Antibody

Binding Specificity: Middle Region

Sequence: SEHRPKIKSE HPGLSIGDTA KKLGEMWSEQ SAKDKQPYEQ KAAKLKEKYE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMGB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HMGB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 209 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Alternative Name: HMGB2

Background: HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this
Alias Symbols: HMG2
Protein Interaction Partner: PKNOX1, UBC, EED, YWHAG, PGD, LDHB, CKB, HMGA1, GZMK, GZMA, CSNK1A1, FN1, SCAF8, APP, TFAP4, CDK2, BKRF1, Cebpb, ELAVL1, HMGB1, CHAF1A, CREBBP, SET, PGR, POU3F1, PRKDC, TP53, RAG1, POU5F1, POU2F2, POU2F1, APEX1, AR, NR3C1,
Protein Size: 209

Molecular Weight: 24 kDa

Gene ID: 3148

NCBI Accession: NM_002129, NP_002120

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin